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12 Ağustos 2013 Pazartesi

Protein reduces endurance (in mice), food processing vs food refining & Schrödinger.

I saw the following study via Twitter. Dietary protein decreases exercise endurance through rapamycin-sensitive suppression of muscle mitochondria.
Mmm, protein!
Hmmm! In mice, a high protein diet significantly decreased the amount of muscle mitochondria, the mitochondrial activity and the running distance at 50 weeks, although it increased muscle mass and grip power.

A mouse's natural diet is fruit or grain from plants, though mice will eat virtually anything, including Kevlar insulation on wiring. Fruit & grains aren't particularly high in protein, so it's quite possible that eating a sub-optimal diet results in sub-optimal health.

If the results do translate to humans, we have a choice between endurance, and muscle mass & strength in our old-age. I know which I would choose. You'll have to prise the proteins from my cold, dead fingers!

More from TwitterA Major Communication Challenge of Our Times: What on Earth Do We Say About Processed Foods? The word "refine/refined" doesn't appear in the above article. I don't have a problem with food processing. What I do have a problem with is food refining. Just after the Mid-Victorian period, it became fashionable to eat foods that had been stripped of "impurities". Goodbye essential co-factors. Hello, degenerative diseases.

Finally, today is the 126th anniversary of Erwin Schrödinger's birthday. I have only one comment:-
Blatantly stolen from http://memegenerator.co/instance/31138345
:-)

31 Temmuz 2013 Çarşamba

Completing the trine: vive la différence!

First, the obligatory picture of Hannah Spearritt :-)
Women have a harder time losing weight than men. Women retain water more than men for hormonal reasons, but a factor that's overlooked is that, on average, healthy women have higher body-fat percentages than healthy men. This is because women have babies and men don't. Who knew? On the plus side, women produce more DHA than men.

Why should having higher body-fat percentages make a difference to weight loss? See What is the required energy deficit per unit weight loss? The energy deficit required to lose 1lb of body-weight increases with increasing body-fat percentage. It's rarely 3,500kcals per lb.

If you really love mathematics, see The Dynamics of Human Body Weight Change by Carson C. Chow and Kevin D. Hall.

From the above paper:- ΔU = ΔQ - ΔW

where ΔU is the change in stored energy in the body, ΔQ is a change in energy input or intake, and ΔW is a change in energy output or expenditure. This is the Energy Balance Equation. As I said back in Back to black, CIAB, pharmaceutical drug deficiencies & nerds.

Where body weight is concerned, calories count (but don't bother trying to count them).
Where body composition is concerned, partitioning counts.
Where health is concerned, macronutrient ratios, EFAs, minerals, vitamins & lifestyles count.

N.B. Poor health can adversely affect body weight and/or body composition, by increasing appetite and/or by adversely affecting partitioning.

24 Temmuz 2013 Çarşamba

Back to black, CIAB, pharmaceutical drug deficiencies & nerds.

First, a song by someone who should be alive, but isn't...

The above video was inspired by a Facebook friend who had an accident with Schwartzkopf black hair dye and spent ages getting the stains off her skin. You know who you are!

I may have mentioned that nutrient deficiencies can adversely affect mental (and/or other) function. Nowadays, many people live on a diet of Crap-In-A-Bag (CIAB). There's just enough essential amino acids (EAAs), essential fatty acids (EFAs), minerals & vitamins to keep their bodies alive. However, Alive ≠ Working properly.

To compensate for one (or more) nutrient deficiencies, many people are prescribed one (or more) pharmaceutical drugs to tweak how their brains work e.g. fluoxetine, citalopram/escitalopram, venlafaxine, quetiapine, risperidone, valproate etc. There are no pharmaceutical drug deficiencies!

There are people who suffer from mental (and/or other) illnesses, despite having diets & lifestyles that provide sufficient amounts of all nutrients. This post isn't about them. There are people who suffer from depression due to traumatic & inescapable events/situations. This post isn't about them, either.

Finally, nerds! We nerds love to compile information. For an interesting interview with a top compiler of useful information, see Examine's Supplement Goals Reference Guide.

For an excellent article with a mere 148 references, see Why Calories Count. To sum up:-

Where body weight is concerned, calories count (but don't bother trying to count them).
Where body composition is concerned, partitioning counts.
Where health is concerned, macronutrient ratios, EFAs, minerals, vitamins & lifestyles count.

N.B. Poor health can adversely affect body weight and/or body composition, by increasing appetite and/or by adversely affecting partitioning.

Continued on Chow on chow, Parkinson's Law, two ways of doing something, and love.

7 Temmuz 2013 Pazar

Sunday Smörgåsbord: liberty, the internet, worry, health & Lyle McDonald.

Five items this time, not necessarily related.
From http://en.wikipedia.org/wiki/Smörgåsbord
By liberty, I mean personal liberty. I believe that individuals should be free to do whatever they want, provided that they don't harm another individual. However, collections of individuals should not be free to do whatever they want, as collections of individuals (i.e. businesses) usually try to profit from individuals, so the welfare of the individual isn't of importance. Businesses obviously don't want to instantly kill their customers, as that's obvious and will probably get them sued. However, "killing them softly" isn't obvious!

In the EC, just about everything has a CE kite-mark in order that it may be sold in the EC. Standards include EMC (Electro-Magnetic Compatibility) to ensure that:-
a) Devices don't emit excessive levels of RF "radiation", which may interfere with other devices.
b) Devices don't respond to excessive levels of RF "radiation", which may interfere with their operation.
I put "radiation" in quotes, as it's TEM (Transverse Electro-Magnetic) radiation i.e. Radio Waves.

In the US, who knows?

This is about "Smart Meters" - again! I've recently seen a surge in Facebook statuses about Smart Meters. I posted a technical article about these devices in Smart meters. Even after I posted a link on Facebook to my article, links to alarmist pages still appeared. The latest one is The Great “Smart Meters” Hoax. Electromagnetic Fields Are Real And Dangerous To Our Health, where Sam Milham, MD, MPH epidemiologist & researcher tells us how things really are.

Unfortunately, he's talking shite. The problem with people talking alarmist shite on the internet is that people who read alarmist internet shite and who are ignorant of the subject, believe it! This causes Fear, Uncertainty & Doubt (FUD), which in turn causes chronic worry. Chronic worry causes chronic hypercortisolaemia, which isn't good. A placebo (e.g. wrapping aluminium foil around your Smart Meter or paying for a "proper" solution to the non-existent problem) alleviates the chronic worry, which improves health.

I don't know about US Smart Meters. For all I know, some eejit has designed them to transmit 1,000W of RF (I'm just being silly), to get an outdoor range of >100miles. As these devices are designed for short-range communication, they probably transmit up to 100mW (about the same power level as WiFi) to get an outdoor range of ~150m. 1mW is one thousandth of a Watt. Transmitting more power than is necessary increases the probability of interference to other electronic devices.

100mW is a lot lower than the power transmitted by mobile phones (up to 2,000mW for the 850/900MHz Vodafone/O2 network), which need to be able to reliably communicate with the nearest mast, which may be miles away. As mobile phones constantly transmit occasional bursts of RF (to let the network know that they are on) and they are either in a pocket or are held against the ear/in front of the face to make/receive calls etc (while transmitting regular bursts of RF) and they are safe to use, how can a Smart Meter which is transmitting a much lower power level at a much greater separation be harmful? It can't.

With WiFi, Equivalent isotropically radiated power (EIRP) in the EU is limited to 100mW. Dunno about the US. Bluetooth is very-low-power (~1mW for Class 3 devices).

So stop worrying! Chronic worry (also, reading alarmist internet shite) is bad for your health.

Finally, I noticed that Evelyn Kocur "liked" an article that I'd read and completely forgotten about. It's Evidence From the Metabolic Ward: 1.6-2.4g/kg Protein Turn Short Term Weight Loss Intervention into a Fat Loss Diet. Interestingly, the protein intake for optimum body recomposition is 1.6-2.4g/kg LBM. This is equivalent to ~1g/lb LBM, which is the protein recommendation given by Lyle McDonald in his Rapid Fat Loss Handbook. Yup, Lyle was right all along. That amount of protein isn't bad for the kidneys (even 50% more protein than that, isn't bad for the kidneys).