Failure to communicate: How to fix it.

First, a video. I used this video about two and a half years ago.


We communicate with each other verbally and non-verbally. To maintain a reasonable rate of information flow from talker to listener, non-verbal handshaking from listener to talker is used for flow-control.

Unfortunately, people with an Autism Spectrum Disorder (ASD) like me (I was officially diagnosed as having an ASD, yesterday) can't detect non-verbal handshaking, resulting in failure to communicate. Body-language = Double-Dutch. This is confusing and upsetting for all concerned, because neither the talker nor the listener understand what's going on.

A talker with an ASD thinks "Why won't they listen to me?". "Why are they walking away?", while a listener without an ASD thinks "Why do they keep on talking when I'm giving clear signs that they should stop?".

Like SkyNet, I have become self-aware. Now that I am aware of this problem, I can fix it. Here's the solution. If you're having a conversation with someone, and they don't stop talking when you're giving clear signs that they should stop, do the following:-

From http://365thingsiloveaboutfrance.com/tag/french-hand-gestures/

Oh, look. The French already do it. From the above site:-
"Chut! / Silence!

When you want some one to shut up or fermez-la, you can hold up your index finger in the air (not in front of your lips), and give a severe look to the people disturbing you. French teachers use this gesture frequently."

Please don't give us a severe look. We don't do it on purpose to annoy you. We can't help it. TIA. :-)

Both Sides Now: Asperger's.

Continued from Both Sides Now: Nerds!

From http://quotes.lifehack.org/quote/bill-gates/be-nice-to-nerds-chances-are-youll/

A couple of years ago, a psychologist that I was chatting to at a party told me that she thought I had Asperger's. I wasn't upset. I was actually rather relieved, as it explained everything. Since then, several more people, who work for "Disability Challengers", working with children with severe ASDs (Autism Spectrum Disorders) have told me much the same thing.

Here's everything(ish)
A preference for reading science books rather than being with people.
A desire to take things apart and put them back together again (sometimes failing at the latter!) to see how they worked.
Being known as "Professor" at school, as I could chatter away about science facts for hours.
Sucking at forming relationships with women. Logic & emotion mixed like oil & water.
Becoming an Electronic Engineer rather than a Doctor, as it meant working with objects rather than people.
Focussing on a task for hours e.g. Researching, producing new blog posts and updating old ones.
Obsessive behaviour in certain areas.
Loving routine.
Hating change.
Difficulty with communicating facts to people e.g. having a "hectoring" tone.
Offending people without realising it by speaking bluntly or interacting with them in a very logical way, and then failing to recognise their body language shouting "Stop talking!", "Go away!", "Why did you do that?", "I'm offended!" etc at me.

In January 2015, after a series of failed relationship attempts, I asked my GP for a referral to an ASD clinic. After a wait of 10 months, I've got an appointment to see an ASD specialist at the end of this month.

Knowing that I would be seen by a specialist made me more self-aware and I started to push myself into doing things that would normally scare the crap out of me e.g. Approaching a complete stranger in a pub, introducing myself and engaging them in meaningful conversation.

So, I know that there's a monkey on my back and I know what it's getting up to an increasing proportion of the time. Bear with, bear with!

By the way, the computer/smart-phone that you're using to read this post was invented/designed/developed by people like me! Ditto, the Internet.

Wheat, Constipation, Ischaemic Heart Disease, Type 1 Diabetes, Schizophrenia and Autism.

Did you see this coming?

Gliadorphin 7, from http://en.wikipedia.org/wiki/Gliadorphin

The above 7-peptide chain contains 3 molecules of proline (the pentagon with a "N" at one corner), just like:-

Bovine β-casomorphin 7, from http://en.wikipedia.org/wiki/Casomorphin

From Further research for consideration in 'the A2 milk case'.
"Prior to discussion it must be clarified that the hypothetical link between A1 consumption with autistic spectral disorder (ASD) and schizophrenia relates not to the cause of the condition but to the aggravation of symptoms associated with these neurological conditions. More specifically, the hypothesis states that the absorption of food-derived exomorphins such as beta casomorphin 7 (BCM 7) may aggravate symptoms associated with ASD or schizophrenia.

This hypothesis is the basis of 'dietary intervention' that excludes gluten and casein (Knivsberg et al., 2002) from the diet of ASD patients. The former, gluten, has been shown to release gliadamorphin, an exomorphin comparable in opioid activity to BCM-7. A number of laboratories in the United States and Europe offer urine tests, which determine the level of peptides including BCM 7 and other beta casomorphins to serve as an indication of the potential usefulness of dietary intervention in the treatment of ASD patients. One published study reports that a casein- and gluten-free diet was accompanied by improvement in 81% of autistic children within 3 months (Cade et al., 2000)."


According to What is gliadorphin?
"What is gliadorphin? Gliadorphin (also called alpha-gliadin or gluteomorphin) is a substance that resembles morphine. Ordinarily, this is a short-lived by-product from the digestion of gluten molecules (found in wheat, barley, rye, oats, and several other grains). Gliadorphin is very similar to casomorphin. Gliadorphin has been verified by mass spectrometry techniques to be present in unusual quantities in urine samples of children with autism, and are believed by many to be a central part of the system of causes and effects that cause autistic development. The most probable reasons for the presence of these molecules are:
* One or more errors in the breakdown (digestion) process caused by enzyme deficiency and/or
* Abnormal permeability of the gut wall (that would allow these relatively large molecules to enter the bloodstream from the intestine in abnormal quantities)."

Continued on Rheumatoid Arthritis: It's the food!

Cow's milk, Schizophrenia and Autism.

As a result of comments to my previous blog post, I did a bit of digging. I dug up something.

From http://en.wikipedia.org/wiki/Milk

Stella Barbone linked to The A2 milk case: a critical review.

This was refuted by A critique of Truswell's A2 milk review.

That referenced Autism and schizophrenia: Intestinal disorders , Can the pathophysiology of autism be explained by the nature of discovered urine peptides? , Enzymatic release of neocasomorphin and beta-casomorphin from bovine beta-casein. & Opioid activities of human b-casomorphin.

Babies have naturally-high gut permeability, so wrong milk proteins may cause damage. Human breast milk contains only A2 casein.

In older humans, gut permeability is modulated by several factors.

1. Insufficient sun exposure, causing hypovitaminosis D. See http://www.ncbi.nlm.nih.gov/pubmed/?term=%22Vitamin+D%22[All+Fields]+AND+%22tight%20junction%22+AND+hasabstract[text]

2. Excessive consumption of oils high in polyunsaturated fatty acids. See Dietary Fat Can Modulate Intestinal Tight Junction Integrity.

3. Excessive consumption of Wheat. See http://www.ncbi.nlm.nih.gov/pubmed/?term=%22Wheat%22[All+Fields]+AND+%22tight+junction%22+AND+hasabstract[text]

4. Excessive exercise. See Shedding Some Light on the Leaky Gut <> Exercise Connection. Plus: 20+ Things You Should or Shouldn't Do to Protect and Restore the Integrity of Your Intestinal Wall.

5. Lack of dietary Sulphur. See Sulphation and Autism: What are the links? A good source of sulphate is Epsom Salts.

See also Physiology and Immunology of Digestion.

Continued on Wheat, Constipation, Ischaemic Heart Disease, Type 1 Diabetes, Schizophrenia and Autism.