Another fallacy promulgated by a certain dietary camp.

High Carb diets are tasteless and monotonous. Steaks, cheeses & butters for the win.

From http://www.slideshare.net/jer04/taiwan-rice-challenge-17671208

If you think that High Carb diets comprise only potatoes, sweet potatoes or rice all day (which some populations actually eat without complaint), then you're mistaken.

Here's a High Carb diet (the food in the picture can sit on top of Basmati rice, if you like).

From http://gluten-free-zen.com/2011/02/13/asian-chicken-wings-vegetable-stir-fry/

Here's another High Carb diet.

From http://bit.ly/1W2fzqh

And another.

From http://www.recipeshubs.com/muesli/18025

And yet another.

From http://www.dreamstime.com/stock-photos-fresh-mixed-fruit-berries-image14688313

The above can be eaten with animal produce, which includes some steaks, cheeses & butters.

Anyone who claims that High Carb diets are tasteless and monotonous has zero imagination.

Why using macronutrient percentages is so wrong.

From http://sciencelearn.org.nz/Contexts/Food-Function-and-Structure/Sci-Media/Images/Macronutrient-percentages

1. Deception

Consider Lies, damned lies and statistics, part n+1. Riera-Crichton et al.  

Relative fat intake in %E decreased and obesity increased.

The conclusion:- "Carbohydrates are fattening and fat is slimming." Yeah, right!

Absolute fat intake in grams/kcals increased after healthy eating guidelines (which weren't low-fat guidelines) came out in 1980, according to More Thoughts on Macronutrient Trends.

Gary Taubes & Nina Teicholz use this deliberate misrepresentation of data to create the false narrative that low-fat healthy eating guidelines caused the obesity epidemic in the US. It's a pack of lies.

2. The terms "Low Fat" and "High Fat" are meaningless

Take 55g of fat (500kcals), 125g of protein (500kcals) and 375g of carbohydrate (1,500kcals). It adds up to 2,500kcals, with a percentage C/F/P split of 60/20/20. It's a High Carb, Low Fat diet.

Now remove 125g of carbohydrate to leave 250g of carbohydrate (1000kcals). It now adds up to 2,000kcals, with a percentage C/F/P split of 50/25/25. It's still a High Carb, Low Fat diet.

Now remove another 125g of carbohydrate to leave 125g of carbohydrate (500kcals). It now adds up to 1,500kcals, with a percentage C/F/P split of 33/33/33. It's now a Medium Carb, Medium Fat Zone diet.

Now remove another 62.5g of carbohydrate to leave 62.5g of carbohydrate (250kcals). It now adds up to 1,250kcals, with a percentage C/F/P split of 20/40/40. It's now a Low Carb, Highish Fat diet.

Now remove another 62.5g of carbohydrate to leave 0g of carbohydrate (0kcals). It now adds up to 1,000kcals, with a percentage C/F/P split of 0/50/50. It's now a Very Low Carb, High Fat diet.

So, 55g/day of fat can be Low Fat, Medium Fat, Highish Fat or High Fat. Which leads to...

3. Confusion

When someone sees the term LCHF (Low Carb, High Fat), they think it means "Eat less carbohydrate and eat more fat". As changes in bodily stores are determined by Energy Balance, eating more fat leads to a slower rate of weight-loss (or even weight-gain), not a faster rate of weight-loss.

By all means cut the consumption of "bad" carbs, like burgers in buns, chips/fries, crisps/chips, pizza, cake, biscuits/cookies, chocolate and sugar sweetened beverages.

However, if you believe that "good" carbs like vegetable produce, legumes, whole grains and whole fruits make you fat and sick, you need to have your head examined, unless you're in the tiny percentage of the population who have genetic carbohydrate intolerance.

See also Insulin Resistance: Solutions to problems.

Everyone is different Part 4, Fallacies and another rant!

Cont'd from Bray et al shows that a calorie *is* a calorie (where weight change is concerned).

The other day, an article about Ruth Frechman appeared in my Facebook News Feed.

See A nutritionist shares pictures of everything she eats in a day

The article (written by an editor, not a dietician) started "If you're trying to eat right, then following the diet of a nutritionist is probably a good start." This infers that everyone should eat the same diet and that diet is what Ruth Frechman ate on that particular day.

Uh, nope! This doesn't follow. The whole article is based on a non sequitur fallacy.

From the reactions on Facebook, you'd think that Ruth Frechman had just admitted to being a serial kitten-murderess. The link to the above article had the following accompanying text:-
"Imagine booking an appointment to see a nutritionist in the hope that it would improve your health and appearance...

And this haggard looking, snack-munching zombie greeted you at her office."
Dismissing someone's knowledge because of their diet and/or appearance is an ad hominem fallacy.

I posted the following status:-
"As I'm unable to leave comments on that News Feed item, I'm sharing it, with the following observations.
1. Dismissing a person's knowledge because of what they look like is an ad hominem fallacy.
2. Insults are scraping the bottom of the debating barrel. Stay classy!
3. The main reason people go to a dietician is because they are fatter than they want to be. If YOUR logic is that a person should look as though they're implementing their weight-loss knowledge and it works, would YOU get weight-loss advice from the man in the blue shirt?
http://i.ytimg.com/vi/sIrXqvtuBo4/maxresdefault.jpg
EDIT: Also https://igcdn-photos-a-a.akamaihd.net/hphotos-ak-xfa1/t51.2885-15/sh0.08/e35/p640x640/11380280_1078302272204224_535077602_n.jpg"

Yesterday, the following post appeared in my News Feed:-
https://www.facebook.com/rannoch.donald/posts/10156093095785104
"In an article worthy of the Onion, Ruth Frechman provides conclusive proof that being a registered dietitian nutritionist means absolutely nothing. But wait...she is the author of that dietary classic "The Food Is My Friend Diet"

The very fact that this person has some degree of qualification and the implied authority that goes along with it suggests that we have reached the apex of nutritional stupidity and ignorance. The fact that Business Insider deem this worth sharing tells us they should stick to what they know.

So, join us as we snack on Popcorn, eat M&Ms, chug down fortified fruit juice, eat Quest bars and chewing gum...

There is an actual meal in there at one point, but it looks decidedly like something you might feed your dog, food is obviously not her friend, it's her fix.

Frechman, by her own account, seems to spend her days stressed, tired and hungry, and feels suitably entitled to share her own brand of self loathing with anyone who will part with the $.

Cut out the static. Learn to cook. Go for a walk. Breathe."

Uh, nope! We don't know how busy Ruth Frechman is, how much free time she has, what facilities she has for preparing meals and what foods she likes to eat. She's criticised for eating treats like popcorn and M&Ms, even though she's slim and apparently in good health.

Here's a link to her book:- http://www.amazon.co.uk/The-Food-Is-Friend-Diet/dp/0984597913#reader_0984597913 Go to Page 33 and criticise THAT.

I can only conclude from some of the comments left on the above Facebook post that the world has a lot of judgemental arseholes.

How we lose weight: Oxidation of carbohydrate & fat in the body.

1. Oxidation of Carbohydrate in the body.

Glucose is C6H12O6, or 6(CH2O)

6(CH2O)+ 6(O2) → 6(CO2) + 6(H2O) + energy

Oxygen is inhaled. Carbon Dioxide is exhaled. Water is lost in breath, wee, poo, sweat & other bodily fluids.

As 6 molecules of Oxygen produce 6 molecules of Carbon Dioxide, the Respiratory Exchange Ratio (RER) is 6/6 = 1

Converting molecular weights into their gram equivalents, 180g of Glucose combines with 192g of Oxygen to produce 264g of Carbon Dioxide plus 108g of water plus ~3,012kJ of energy. I'm using kJ rather than kcal, as the human body expends energy as mechanical energy (force x distance) and heat energy.

2. Oxidation of Fat in the body.

Fat is three fatty acids (Stearic Acid, say) attached to a Glycerol backbone. As ~95% of the energy released from a fat is from the three fatty acids, I'm ignoring the Glycerol backbone, to keep the maths as easy as possible.  Stearic Acid is CH3(CH2)16COOH. I'm approximating it to 18(CH2), to keep the maths as easy as possible.

54(CH2) + 81(O2) → 54(CO2) + 54(H2O) + energy

Oxygen is inhaled. Carbon Dioxide is exhaled. Water is lost in breath, wee, poo, sweat & other bodily fluids.

As 81 molecules of Oxygen produce 54 molecules of Carbon Dioxide, the RER is 54/81 = 0.67

Note: The RER for fats is actually 0.7, as the Glycerol backbone is converted into Glucose by the liver. As the RER for  Glucose is 1, this raises the RER of my approximated fat by ~5%.

Converting molecular weights into their gram equivalents, 756g of approximated fat combines with 2,592g of Oxygen to produce 2,376g of Carbon Dioxide plus 972g of water plus ~28,468kJ of energy.

We lose weight by breathing, weeing, pooing, sweating etc. See also Majority of weight loss occurs 'via breathing'.

This doesn't invalidate Energy Balance, as the kcal/kJ values for foods merely represents the amount of chemical energy that can be released by oxidation of the various fuels in the foods. See Why Calories count (where weight change is concerned).

We gain weight by consuming fuels & water.

Variations in weight change for a given Calorie change - An Engineer's Perspective.

Another techie post, inspired by Insulin Doesn't Regulate Fat Mass. Consider the inverting amplifier using an Op-Amp, below:-

From HERE

As the amplifier is inverting (i.e. a ↑ input on V_in results in a ↓ output on V_out), the feedback from V_out via R₂ opposes V_in via R₁ at the - terminal of the Op-Amp.

If R1 = R2 and V_in changes from 0V to 1V, the change in V_- (the voltage on the - terminal of the Op-Amp) varies with A (the magnitude of the Op-Amp gain) as follows*:-

A_____________Change in V_-(V)
∞_____________0
1,000,000_____~0.000001
1,000_________~0.001
100___________~0.01
10____________~0.08
8_____________0.1
5_____________~0.14
3_____________0.2
2_____________0.25
1_____________~0.33
0_____________0.5

As the body operates on biochemical principles, slopes of input/output transfer functions aren't steep at their steepest points. E.g.

From http://bja.oxfordjournals.org/content/85/1/69.long

Therefore, the gains in the various parts of the Leptin "adipostat" NFB loop are not very high. Therefore, there will be a significant variation in weight change vs Calorie change, and there will be significant variations in the variation due to loop gain variations from person to person.

Insulin Resistance makes the slopes of  the above input/output transfer functions shallower, reducing the gain in the system. This increases the variation in weight change vs Calorie change. For ways to reduce Insulin Resistance, see Insulin Resistance: Solutions to problems.

*In case anyone thinks that I've made the numbers up, here's the maths:-
Current in/out of the - terminal of the Op-Amp = 0.
∴ I_R1 = I_R2
I set R1 = R2 to keep the maths simple. By Ohm's Law, V = I * R.
∴ V_R1 = V_R2
With a 0V input:-
All currents & voltages = 0.

With a 1V input:-
V_R1 = 1 - V_-
V_R2 = V_- - V_out.  As V_out is negative, - V_out is positive.
- V_out = A * V_-
∴ V_R2 = V_- + (A * V_-)
∴ 1 - V_- = V_- + (A * V_-)
Rearranging:-
1 = (2 * V_-) + (A * V_-)
Dividing both sides by V_-:-
(1/V_-) = 2 + A
∴ V_- = 1/(2 + A)

Is the world getting better, or worse?

A few days ago, on Facebook, the following graphic caught my eye.

From http://www.businessinsider.com/the-world-is-becoming-a-better-place-2014-10#ixzz3HumR3IGy

Average life expectancy in England in 1843 was only 40 years. According to How the Mid-Victorians Worked, Ate and Died., those who survived being born, accidents & infections in the first five years of life lived to a ripe old age, despite no modern drugs or other medical technology.

This suggests that mortality between the ages of zero to five was ~50% back then. Yikes.

Click the link in the caption to see other ways in which the world has got better.

Fibromyalgia: It's the food, again! (probably).

From http://stickmancommunications.co.uk/Keyring-Card-Fibromyalgia

Serendipity strikes again! On Facebook, I saw https://www.facebook.com/PaleoDietNewZealand/posts/763653980371516 . That linked to Fibromyalgia and non‑celiac gluten sensitivity: a description with remission of fibromyalgia.

For people unfamiliar with scientific terms, here are some definitions:-
Non-celiac gluten sensitivity: A reaction to gluten, not due to Celiac (Coeliac in the U.K.) Disease.
Remission: (medicine) An abatement or lessening of the manifestations of a disease.

So, is Gliadorphin-7 (formed during the digestion of gluten) to blame?

Probably.

Could Beta CasoMorphin-7 (formed during the digestion of A1 cow's milk) also be a problem?

Possibly.

Is Increased/Excessive Intestinal Permeability allowing the above large molecules to pass through insufficiently tight junctions?

Definitely, maybe.

Is there really no cure for Fibromyalgia? It's possible to tighten-up insufficiently tight junctions. Insufficiently tight junctions can be caused by:-

1. Insufficient sun exposure, causing hypovitaminosis D. See http://www.ncbi.nlm.nih.gov/pubmed/?term=%22Vitamin+D%22[All+Fields]+AND+%22tight%20junction%22+AND+hasabstract[text]

2. Excessive consumption of oils high in polyunsaturated fatty acids. See Dietary Fat Can Modulate Intestinal Tight Junction Integrity.

3. Excessive consumption of Wheat. See http://www.ncbi.nlm.nih.gov/pubmed/?term=%22Wheat%22[All%20Fields]%20AND%20%22tight%20junction%22[All%20Fields]%20AND%20hasabstract[text]%20AND%20%22humans%22[MeSH%20Terms]

4. Excessive exercise. See Shedding Some Light on the Leaky Gut <> Exercise Connection. Plus: 20+ Things You Should or Shouldn't Do to Protect and Restore the Integrity of Your Intestinal Wall.

5. Lack of dietary Sulphur. See Sulphation and Autism: What are the links? A good source of sulphate is Epsom Salts.

See also Physiology and Immunology of Digestion.

And finally...
If a science person ever tells you "Increased/Excessive Intestinal Permeability a.k.a. "Leaky gut" just doesn't exist because, you know, I'm a scientist.", point out that it's an Appeal from authority fallacy, and demand that they provide high quality evidence to support their statement.

Because, you know, I'm a retired Electronic Engineer! :-)